Vi-CELL BLU vs. Vi-CELL XR: Comparison of System Specifications
Based on customer feedback, we made these enhancements for Vi-CELL BLU cell viability analyzer:
- Compatibility with a 96-well plate
- Carousel accommodates more sample cups
- Faster sample processing time
- Smaller sample volume required
- Easier reagent loading
- Take up less bench space with monitor incorporated in system
- Facilitates 21 CFR Part 11 compliance
The Vi-CELL BLU automates the trypan blue dye exclusion method for cell viability and counting using advanced liquid handling and imaging technology for applications in biopharmaceutical quality control and pharmacology. With the Vi-CELL BLU you automate the entire analysis process – sample aspiration, trypan blue mixing, image analysis and instrument cleaning – to revolutionize the speed, reliability and reproducibility of results, and it provides critical information manual cell counting methods simply cannot offer.
| Criteria | Vi-CELL XR | Vi-CELL BLU |
|---|---|---|
| Single sample analysis time | 180 sec | < 130 sec Normal Mode < 90 sec Fast Mode |
| Carousel loading | 12 position carousel | 24 position carousel |
| Microplate loading | - | Standard multi–well microplates |
| Cell Viability Method | Trypan blue dye exclusion | Trypan blue dye exclusion |
| Cell Size Range | 2–70 μm | 2–60 μm |
| Focus System | Autofocus | Autofocus |
| Image Transfer | Firewire | USB 3.0 |
| Camera Sensor Size | 1280x960 | 2048x2048 |
| Captured Image Size | 882x661 pixels | 2048x2048 |
| Analyzed Image Dimensions | 832x611 μm | 1000x1000 μm |
| Effective Resolution | 1 μm per pixel | 0.5 μm per pixel |
| Imaged volume per frame | 43 nL | 65 nL |
| Minimum Sample Volume | 500 μL | 200 μL Normal Mode 170 μL Fast Mode |
| Cell Density Range | 5x104 – 1x107 cells/mL | 5x104 – 1.5x107 cells/mL |
| Counting Accuracy | ± 10% | ± 10% |
| Counting repeatability | ± 10% | ± 5% |
| Reagent Pack | 200 activities per pack | 310 activities per pack |
| Facilitates 21 CFR Part 11 compliance | Yes | Yes |
| Data formats | TXT, MS Excel | CSV, PDF, Encrypted Binary |
| Touchscreen interface | Depends on external PC | Integrated |
| SQL compatible database | No | Yes |
| Single Sign-On (SSO) | No | Yes |
| Computer System | External PC, Windows 7 Professional | Integrated PC, Windows 10 Enterprise LTSC, 64 bit |
| Computer System Specifications | Varies depending on configuration ordered | 6th i7–6700 Generation Intel CPU 4 cores at 3.4 GHz 16 GB DDR4–2400 RAM Mini–ITX Motherboard 500 GB Samsung EVO 850 SSD |
| Connectivity | Via PC system | 2 x USB 3.0 ports, Gigabit Ethernet |
| Height | 44.5 cm (17.5 in) excluding PC | 45 cm (16.5 in) |
| Width | 38 cm (15 in) excluding PC | 54 cm (21 in) |
| Depth | 41 cm (16 in) excluding PC | 42 cm (18 in) |
| Weight | 11.3 Kg (25 lb) excluding PC | 28 Kg (63 lb) |
| Power | 41 cm (16 in) excluding PC | 42 cm (18 in) |
| Depth | Power: 50 watts (65 watts max) Voltages: 100V, 120V, 220V, or 240 V50/60 Hz | Power: 50 watts (65 watts max) Voltages: 100V, 120V, 220V, or 240 V50/60 Hz |
