A comprehensive guide to extracellular vesicle counting, size determination, and characterization

Flow cytometry enables sensitive, consistent, and flexible EV analysis:

  • EVs mediate cell-cell communication in the human body. Studying them can help researchers understand and characterize physiological mechanisms as well as diseases, and develop new treatments.

  • To thoroughly understand EVs, researchers must be able to quantify them with count and concentration, determine their size and characterize them.

  • Many techniques can be used to analyze EVs, including some that can provide a combination of counting, size and characterization - but each has drawbacks.

  • Nanoscale flow cytometry is emerging as a tool to bring depth, efficiency, and quality to EV research, enabling analysis of even small EVs. 

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