DURAClone IF Basophil Activation
Basophils play a key role in immediate hypersensitivity, often referred to as allergy. Upon specific recognition of allergens by surface IgE, basophils release potent mediators, accompanied by mechanistically distinct surface expression of activation markers CD63 and CD203c. The DURAClone IF Basophil Activation panel assesses these antigens, indicating IgE-mediated activation. It utilizes dry reagent technology that confers workflow improvements.
- Panel of 5 markers in fluorochrome combinations that provide robust population identification, including CD3, CD45, CD63, CD203c and CD294
- Pre-formulated antibody panel in a unitized assay eliminating antibody cocktailing
- 25 tests per kit including 3 compensation kits with lot matched tandem dyes
For Research Use Only. Not for use in diagnostic procedures.
Features
Expert Panels
- Proven marker combination to identify basophils and to characterize IgE-mediated basophil activation
- Open channels to add drop-in markers to modify for different research questions
- Designed for assay precision and lot-to-lot consistency
Efficiency
- Eliminate time spent in titrating different antibody lots
- Avoid waste that comes from preparing cocktail master mix
- Simplify inventory management
Consistency
- Unitized assays eliminate error prone pipetting steps
- Includes lot matched tandem dyes for compensation controls for improved accuracy
- Dry format maintains reagent performance better than liquid under stress conditions
Easy to Use
- Ready to use assay with verified panel design
- Includes sample preparation and staining procedure
- Streamlined workflow, just add sample, incubate, wash and acquire
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Technical Documents
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