Valita Aggregation Pure Assays to Determine Antibody Aggregation
Results in minutes not hours.
The Valita Aggregation Pure assay is a plate-based, 96‑well screening tool that offers rapid, high-throughput antibody aggregation detection and quantification. It is among the fastest and simplest aggregation detection tools on the market and is compatible with high-performance microplate readers with Fluorescence Polarization functionality.
- Simple & fast
- Measure aggregates during monoclonal antibody manufacturing
- Enhance your process development workflow
Application Notes
- The Valita Aggregation Pure assay: A rapid and accurate alternative for aggregation quantification of purified monoclonal antibodies
- Performance of the Valita Aggregation Pure assay vs HPLC-SEC
Features of Valita Aggregation Pure Assay
Simply measure IgG aggregation
- No wash steps required
- No additional reagents needed
- Only requirement: plate reader optimized for fluorescence polarization
Results in minutes, not hours
- Simple: add, mix and read
- Rapid: results in less than 15 minutes
- Automation friendly: 3 steps in standard 96-well plates
- Value for money: competition-beating prices
Rapid & easy to use
- Fast and easy quantification of aggregated IgG
- Less complexity saves time compared to DLS/SLS or HPLC SEC
Technical features
- In 96-well plate format
- Recommended sample concentration of 200 mg/L to 2 g/L
- Assay accuracy of > 95 % for human IgG1 samples with levels of aggregation > 0.5 % at 1 g/L
- Fluorescent binding peptide with excitation max = 560 nm and emission max = 590 nm
Introducing the Valita Aggregation Pure Assay
Explore how the Valita Aggregation Pure assay can reduce costs and time-to-market in your monoclonal antibody manufacturing processes by optimizing the process development workflow.
Learn More about the Valita Aggregation Pure Assay
Valita Aggregation Pure Assay
Technical Documents