Nanoparticle Research

Leverage the power of flow cytometry for the detection and characterization of cellular origin nanoparticles

Interest in nanoparticles and extracellular vesicles of cellular origin is exploding due to new insights into the role these particles play in extracellular communication processes and the potential for detecting pathological states via liquid biopsy.

Several fundamental capabilities of flow cytometry make this an attractive platform for extracellular vesicle research, such as the ability to detect large numbers of events and discriminate rare events while collecting information on surface composition.

Recent developments in laser and electronics design pushed the boundaries of reliably detecting events in the nanoparticle size range. The newest member of the CytoFLEX Platform, the CytoFLEX nano Flow Cytometer is the first benchtop instrument with acceptable noise-to-signal discrimination for the reliable detection of particles down to 80 nm. 

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Physical and Chemical Characterization of Nanoparticle Constructs Using the Analytical Ultracentrifuge Webinar covers physical and chemical characterization of nanoparticle constructs using analytical ultracentrifugation. Webinar is presented by Osman M Bakr from King Abdullah University of Science and Technology. 
Analytical Ultracentrifugation in Nanoparticle Analysis Joshua Robinson covers the utility of fractionation in the investigation of complex mixtures and polydisperse samples as well as versatility of analytical ultracentrifugation (AUC) for colloid chemistry. He quickly reviews analytical ultracentrifugation (AUC) theory, then discusses deconstructing nano-constructs and how AUC has been used in recent literature to really probe the underlying structure of nano-constructs, nanomaterials. Other topics covered include nanoparticle sample preparation, as well as Beckman Coulter's research and future perspectives.
Quantitative Determination of Reaction Stoichiometry, Interaction Energies, and Solute Masses Using Analytical Ultracentrifugation Live broadcast covering applications of analytical ultracentrifugation (AUC). 
Following isolation, what are the main methods for analyzing EVs? Methods for extracellular vesicle analysis.
Does this tech apply for follicular fluid samples?

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