Nanoparticle Research

Leverage the power of flow cytometry for the detection and characterization of cellular origin nanoparticles

Interest in nanoparticles and extracellular vesicles of cellular origin is exploding due to new insights into the role these particles play in extracellular communication processes and the potential for detecting pathological states via liquid biopsy.

Several fundamental capabilities of flow cytometry make this an attractive platform for extracellular vesicle research, such as the ability to detect large numbers of events and discriminate rare events while collecting information on surface composition.

Recent developments in laser and electronics design pushed the boundaries of reliably detecting events in the nanoparticle size range. The newest member of the CytoFLEX Platform, the CytoFLEX nano Flow Cytometer is the first benchtop instrument with acceptable noise-to-signal discrimination for the reliable detection of particles down to 80 nm. 

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Characterizing the Light-Scatter Sensitivity of the CytoFLEX Flow Cytometer The CytoFLEX is so sensitive that the SSC detector actually has an attenuation filter to reduce 95% of the scatter signal, adjusting it to a range useful for cells
Preparing a CytoFLEX for Nanoscale Flow Cytometry In this poster, we will demonstrate how to properly setup and clean a CytoFLEX flow cytometer for NP analyses

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