2022 |
Best Practices for Aggregate Quantitation of Antibody Therapeutics by Sedimentation Velocity Analytical Ultracentrifugation |
Journal of Pharmaceutical Sciences |
George M. Bou-Assaf, Ivan L. Budyak, Michael Brenowitz, Eric S. Day, David Hayes, John Hill, Ranajoy Majumdar, Paola Ringhieri, Peter Schuck, Jasper C. Lin |
doi.org/10.1016/j.xphs.2021.12.023 |
2022 |
Multi-wavelength analytical ultracentrifugation of biopolymer mixtures and interactions |
Analytical Biochemistry |
Amy Henrickson, Gary E. Gorbet, Alexey Savelyev, Minji Kim, Jason Hargreaves, Sarah K. Schultz, Ute Kothe, Borries Demeler |
doi.org/10.1016/j.ab.2022.114728 |
2021 |
Density Matching Multi-wavelength Analytical Ultracentrifugation to Measure Drug Loading of Lipid Nanoparticle Formulations |
ACS Nano |
Amy Henrickson, Jayesh A. Kulkarni, Josh Zaifman, Gary E. Gorbet, Pieter R. Cullis, Borries Demeler |
doi.org/10.1021/acsnano.0c10069 |
2021 |
Reincarnation of the Analytical Ultracentrifuge: Emerging Opportunities for Nanomedicine |
Analytical Chemistry |
Olenka Jibaja Valderrama and Ivo Nischang |
doi.org/10.1021/acs.analchem.1c03116 |
2021 |
Comprehensive Size Distribution and Composition Analysis of Adeno-Associated Virus Vector by Multiwavelength Sedimentation Velocity Analytical Ultracentrifugation |
Journal of Pharmaceutical Sciences |
Takahiro Maruno, Kaede Usami, Kentaro Ishii, Tetsuo Torisu, Susumu Uchiyama |
doi.org/10.1016/j.xphs.2021.06.031 |
2021 |
Analytical Ultracentrifugation for Analysis of Protein-Nucleic Acid Interactions |
Methods of Molecular Biology |
Andrea Bogutzki and Ute Curth |
doi.org/10.1007/978‑1‑0716‑1197‑5_19 |
2021 |
Analytical Ultracentrifugation as a Matrix-Free Probe for the Study of Kinase Related Cellular and Bacterial Membrane Proteins and Glycans |
Molecules |
Stephen E. Harding |
doi.org/10.3390/molecules26196080 |
2021 |
Boundary convection during sedimentation velocity in the Optima analytical ultracentrifuge |
Analytical Biochemistry |
Steven A. Berkowitz and Thomas Laue |
doi.org/10.1016/j.ab.2021.114306 |
2021 |
Analytical band centrifugation for the separation and quantification of empty and full AAV particles |
Molecular Therapy – Methods & Clinical Development |
Harshit Khasa, Greg Kilby, Xiaoyu Chen, Chunlei Wang |
doi.org/10.1016/j.omtm.2021.04.008 |
2020 |
Analytical ultracentrifuge: an ideal tool for characterization of non-coding RNAs |
European Biophysics Journal |
Maulik D. Badmalia, M. Quadir Siddiqui, Tyler Mrozowich, Darren L. Gemmill, Trushar R. Patel |
doi.org/10.1007/s00249‑020‑01470‑9 |
2020 |
High-resolution structure and biophysical characterization of the nucleocapsid phosphoprotein dimerization domain from the Covid-19 severe acute respiratory syndrome coronavirus 2 |
Biochemical and Biophysical Research Communications |
Luca Zinzula, Jerome Basquin, Stefan Bohn, Florian Beck, Sven Klumpe, Günter Pfeifer, István Nagy, Andreas Bracher, F. Ulrich Hartl, Wolfgang Baumeister |
doi.org/10.1016/j.bbrc.2020.09.131 |
2020 |
Measuring aggregates, self-association, and weak interactions in concentrated therapeutic antibody solutions |
mAbs |
Sumit K. Chaturvedi, Arun Parupudi, Kristian Juul-Madsen, Ai Nguyen, Thomas Vorup-Jensen, Sonia Dragulin-Otto, Huaying Zhao, Reza Esfandiary, Peter Schuck |
doi.org/10.1080/19420862.2020.1810488 |
2020 |
Moving analytical ultracentrifugation software to a good manufacturing practices (GMP) environment |
PLOS Computational Biology |
Alexey Savelyev, Gary E. Gorbet, Amy Henrickson, Borries Demeler |
doi.org/10.1371/journal.pcbi.1007942 |
2020 |
Analytical ultracentrifugation: still the gold standard that offers multiple solutions |
European Biophysics Journal |
Renwick C. J. Dobson and Trushar R. Patel |
doi.org/10.1007/s00249‑020‑01483‑4 |
2020 |
Quantitation of soluble aggregates by sedimentation velocity analytical ultracentrifugation using an optical alignment system – Aspects of method validation |
Analytical Biochemistry |
Brandon L. Doyle, Adam P. Rauk, William F. Weiss 4th, Ivan L. Budyak |
doi.org/10.1016/j.ab.2020.113837 |
2020 |
A comparison of data quality using quartz vs. sapphire cell windows in analytical ultracentrifugation |
European Biophysics Journal |
Akash Bhattacharya and Eric Von Seggern |
doi.org/10.1007/s00249‑020‑01454‑9 |
2019 |
Optimized filopodia formation requires myosin tail domain cooperation |
Proceedings of the National Academy of Sciences |
Ashley L. Arthur, Livia D. Songster, Helena Sirkia, Akash Bhattacharya, Carlos Kikuti, Fernanda Pires Borrega, Anne Houdusse, Margaret A. Titus |
doi.org/10.1073/pnas.1901527116 |
2018 |
Precise determination of protein extinction coefficients under native and denaturing conditions using SV-AUC |
European Biophysics Journal |
Andreas Hoffmann, Kerstin Grassl, Janine Gommert, Christian Schlesak, Alexander Bepperling |
doi.org/10.1007/s00249‑018‑1299‑x |
2018 |
Multi-wavelength analytical ultracentrifugation of human serum albumin complexed with porphyrin |
European Biophysics Journal |
Courtney N. Johnson, Gary E. Gorbet, Heidi Ramsower, Julio Urquidi, Lorenzo Brancaleon, Borries Demeler |
doi.org/10.1007/s00249‑018‑1301‑7 |
2018 |
Analytical ultracentrifugation (AUC): a seminal tool offering multiple solutions |
European Biophysics Journal |
Olwyn Byron, Ivo Nischang, Trushar R. Patel |
doi.org/10.1007/s00249‑018‑1333‑z |
2018 |
Universal Method for the Purification of Recombinant AAV Vectors of Differing Serotypes |
Molecular Therapy – Methods & Clinical Development |
Shelley A. Nass, Maryellen A. Mattingly, Denise A. Woodcock, Brenda L. Burnham, Jeffrey A. Ardinger, Shayla E. Osmond, Amy M. Frederick, Abraham Scaria, Seng H. Cheng, Catherine R. O’Riordan |
doi.org/10.1016/j.omtm.2017.12.004 |
2015 |
Enrichment and characterization of ferritin for nanomaterial applications |
Nanotechnology |
Rodolfo Ghirlando, Radina Mutskova, Chad Schwartz |
doi.org/10.1088/0957‑4484/27/4/045102 |
2015 |
Characterization of Homogeneous, Cooperative Protein–DNA Clusters by Sedimentation Equilibrium Analytical Ultracentrifugation and Atomic Force Microscopy |
Methods in Enzymology |
Ingrid Tessmer and Michael G. Fried |
doi.org/10.1016/bs.mie.2015.06.036 |
2015 |
Analytical Ultracentrifugation and Its Role in Development and Research of Therapeutical Proteins |
Methods in Enzymology |
Jun Liu, Sandeep Yadav, James Andya, Barthélemy Demeule, Steven J. Shire |
doi.org/10.1016/bs.mie.2015.04.008 |
2015 |
Analytical Ultracentrifugation as an Approach to Characterize Recombinant Adeno-Associated Viral Vectors |
Human Gene Therapy Methods |
Brenda Burnham, Shelley Nass, Elton Kong, MaryEllen Mattingly, Denise Woodcock, Antonius Song, Samuel Wadsworth, Seng H. Cheng, Abraham Scaria, Catherine R. O’Riordan |
doi.org/10.1089/hgtb.2015.048 |
2015 |
Sedimentation Velocity: A Classical Perspective |
Methods in Enzymology |
John J.Correia and Walter F. Stafford |
doi.org/10.1016/bs.mie.2015.06.042 |
2014 |
Characterization of Size, Anisotropy, and Density Heterogeneity of Nanoparticles by Sedimentation Velocity |
Analytical Chemistry |
Borries Demeler, Tich-Lam Nguyen, Gary E. Gorbet, Virgil Schirf, Emre H. Brookes, Paul Mulvaney, Ala’a O. El-Ballouli, Jun Pan, Osman M. Bakr, Aysha K. Demeler, Blanca I. Hernandez Uribe, Nabraj Bhattarai, Robert L. Whetten |
doi.org/10.1021/ac501722r |
2013 |
Overview of current methods in sedimentation velocity and sedimentation equilibrium analytical ultracentrifugation |
Current Protocols in Protein Science |
Huaying Zhao, Chad A. Brautigam, Rodolfo Ghirlando, Peter Schuck |
doi.org/10.1002/0471140864.ps2012s71 |
2011 |
Determination of nanoparticle size distribution together with density or molecular weight by 2D analytical ultracentrifugation |
Nature Communications |
Randy P. Carney, Jin Young Kim, Huifeng Qian, Rongchao Jin, Hakim Mehenni, Francesco Stellacci, Osman M. Bakr |
doi.org/10.1038/ncomms1338 |
2008 |
Analytical ultracentrifugation: sedimentation velocity and sedimentation equilibrium |
Methods in Cell Biology |
James L. Cole, Jeffrey W. Lary, Thomas P. Moody, Thomas M. Laue |
doi.org/10.1016/S0091‑679X(07)84006‑4 |
2007 |
Monitoring the homogeneity of adenovirus preparations (a gene therapy delivery system) using analytical ultracentrifugation |
Analytical Biochemistry |
Steven A. Berkowitz and John S. Philo |
doi.org/10.1016/j.ab.2006.11.031 |
2006 |
Role of Analytical Ultracentrifugation in Assessing the Aggregation of Protein Biopharmaceuticals |
The AAPS Journal |
Steven A. Berkowitz |
doi.org/10.1208/aapsj080368 |
2000 |
Molecular weight determination of membrane proteins by sedimentation equilibrium at the sucrose or Nycodenz-adjusted density of the hydrated detergent micelle |
Biochimica et Biophysica Acta (BBA) - Biomembranes |
Ariel Lustig, Andreas Engel, Georgios Tsiotis, Ehud M. Landau, Werner Baschong |
doi.org/10.1016/s0005‑2736(99)00254‑0 |