Next-Generation Sequencing Library Preparation

Automated Workflow Solutions

Generate High-Quality Data Faster by Automating Your NGS Library Prep

Library preparation is a critical step in next-generation sequencing (NGS), involving the transformation of DNA or RNA samples into fragments ready for sequencing. The accuracy and reliability of the NGS data heavily depend on the quality of the library preparation. One of the most effective ways to obtain robust and high-quality NGS libraries is to automate the preparation process with trusted automated systems.

As a rule, the core component of such a system is an automated liquid handler, as liquid handling is the most time-consuming and error-prone component of the manual NGS library prep process. Supplemented with automatable reagents and integrated devices, automated systems help reduce human error, improve reproducibility, increase lab’s throughput and save money, making the entire process more efficient and reliable.

Scientist exploring NGS data

Our NGS Library Prep Automated Solutions

We offer a wide range of established solutions for customers, scalable from laboratories just starting out with their first preps to cutting-edge sequencing powerhouses. Having harnessed such technologies as tip-based liquid handling, acoustic liquid handling and SPRI bead-based technology, we are a trusted partner in NGS library prep automation.

Click on the 3 light-grey steps of the NGS library prep workflow below to reveal products automating these steps

DNA Extraction Kits

DNA Extraction Kits

RNA Extraction Kits

RNA Extraction Kits

Total Nucleic Acid Extraction Kits

Total Nucleic Acid Extraction Kits

Cleanup and Size Selection Reagents

Cleanup and Size Selection Reagents

Biomek i-Series Automated Workstations

Biomek i-Series Automated Workstations

Biomek NGeniuS Next Generation Library Prep System

Biomek NGeniuS Next Generation Library Prep System

Echo 525 Acoustic Liquid Handler

Biomek Echo One High-Throughput Genomics Bundled Solution

DNA Extraction Kits

DNA Extraction Kits

RNA Extraction Kits

RNA Extraction Kits

Total Nucleic Acid Extraction Kits

Total Nucleic Acid Extraction Kits

Cleanup and Size Selection Reagents

Cleanup and Size Selection Reagents

Biomek i-Series Automated Workstations

Biomek i-Series Automated Workstations

Biomek NGeniuS Next Generation Library Prep System

Biomek NGeniuS Next Generation Library Prep System

Echo 525 Acoustic Liquid Handler

Biomek Echo One High-Throughput Genomics Bundled Solution

DNA Extraction Kits

DNA Extraction Kits

RNA Extraction Kits

RNA Extraction Kits

Total Nucleic Acid Extraction Kits

Total Nucleic Acid Extraction Kits

Cleanup and Size Selection Reagents

Cleanup and Size Selection Reagents

Biomek i-Series Automated Workstations

Biomek i-Series Automated Workstations

Biomek NGeniuS Next Generation Library Prep System

Biomek NGeniuS Next Generation Library Prep System

Echo 525 Acoustic Liquid Handler

Biomek Echo One High-Throughput Genomics Bundled Solution

DNA Extraction Kits

DNA Extraction Kits

RNA Extraction Kits

RNA Extraction Kits

Total Nucleic Acid Extraction Kits

Total Nucleic Acid Extraction Kits

Cleanup and Size Selection Reagents

Cleanup and Size Selection Reagents

Biomek i-Series Automated Workstations

Biomek i-Series Automated Workstations

Biomek NGeniuS Next Generation Library Prep System

Biomek NGeniuS Next Generation Library Prep System

Echo 525 Acoustic Liquid Handler

Biomek Echo One High-Throughput Genomics Bundled Solution

 

Benefits of Our NGS Library Prep Automated Solutions

NGS Cost Icon

Cost-Effectiveness

Gain a new level of cost savings and throughput to increase your lab's profitability

Precise NGS Data Icon

Dependability

Deliver consistent results with confidence by generating high-quality sequencing data every time

NGS Flexibility Icon

Flexibility

Customize and optimize NGS workflows of different throughputs for both standard and reduced reaction volumes

NGS Ease-of-Use Icon

Ease-of-Use

Easily automate NGS workflows with smart software and a library of complimentary demonstrated methods

Our NGS Library Prep Automation Partners

  • Agilent
  • Pillar Biosciences
  • Watchmaker Genomics
  • Illumina
  • New England Biolabs
  • Roche
  • 10X Genomics
  • IDT
  • Oxford Nanopore
  • Qiagen
  • Invitae
  • Twist Bioscience

Featured Resources

 

Brochure

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Flyer

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Biomek NGeniuS Applications

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Method Card

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Method Card

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Hear from Our Customers

John E. Gill

Senior Director of R&D, Codex DNA

At Codex DNA, the Echo 525 Liquid Handler and Access Workstation from Beckman Coulter Life Sciences has become an integral part of our BioXp™ system gene synthesis workflows. Processes that would take 8 hours with traditional liquid handlers now take less than 30 minutes with the Echo [acoustic and tip-less liquid handler], enabling the construction of DNA variant libraries at an unprecedented scale. Moreover, the high accuracy and precision of non-contact acoustic transfers ensure that we’re delivering every oligonucleotide with the utmost confidence.

Dr. Tomasz Zemojtel

Head of Genomics Platform, Berlin Institute of Health (BIH)

A high level of data reproducibility was observed when the library prep workflow was automated on a Biomek i7 Hybrid Workstation.

Rob Cummins

Senior Medical Scientist, Royal College of Surgeons, Ireland

Considering this was my first time to use the software, I found it very intuitive and easy to use. I was impressed with how little data and time input is required from the user to set up a run.

Tony O'Grady

Chief Medical Scientist, Royal College of Surgeons, Dublin, Ireland

The ability to put a DNA sample onto the [Biomek NGeniuS] system and walk away, literally press a button, turn a dial, one dial-there's only one dial to turn on the machine ... press one button-there's only one button to press on it as well-and walk away and come back later that day or the next day because it's up to you when you run it ... it's priceless, really.

Per Hoffman

Laboratory Director, Life and Brain Center, Germany

This instrument [Biomek NGeniuS] is a real milestone in small-scale NGS systems.

Dr. Nallasivam Palanisamy

Associate Scientist, Department of Urology, Henry Ford Health, Detroit, Michigan, USA

For this stage of our prostate cancer research, we successfully used FormaPure XL [reagent kit] to generate whole transcriptome sequencing data for biomarker discovery...

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Not intended or validated for use in the diagnosis of disease or other conditions.

ECHO is a trademark or registered trademark of Labcyte Inc. in the United States and other countries. Labcyte is a Beckman Coulter company.