CD123 (IL-3Rα) Antibodies

The CD123 antigen, alias Interleukin-3 alpha receptor (IL-3Rα), belongs to the cytokine receptor family. It is constitutively expressed by committed hematopoietic stem / progenitor cells, by most of the myeloid lineage (CD13+, CD14+, CD33+, CD15low), and by some CD19+ cells, it is absent from CD3+ cells. CD123 is a useful new marker for distinguishing B-cell disorders with circulating villous lymphocytes.