Echo 学习中心

Better + Together. 2019年，贝克曼库尔特生命科学公司成功收购Labcyte. 这次并购推动 Echo 声波移液系统 d Biomek自动化工作站  工作站的强大技术和功能实现全面整合，开创移液技术应用新局面，广泛应用于药物开发、样品管理、合成生物学、基因组学、蛋白质组学和功能筛选等工作流。

高精准、全自动、非接触式声波移液技术单次移液量低至 2.5 nL。Echo 声波移液系统为科研工作者带来更高精度、更高效率和更可持续的全新移液体验。

Echo Acoustic Liquid Handlers - Beckman Coulter Life Sciences

通过声能转移液体

 

Echo声波移液系统：

  • 声波液滴喷射（ADE）技术精准转移各类液体，速度高达 700 滴/秒
  • Echo 兼容母板至倒置目标微孔板的非接触式移液
  • 动态流体分析（DFA）技术实时调整移液参数，纳升级可靠移液，无需用户干预
  • 精确计算母板孔液体高度，动态分析液体类型，如二甲基亚砜（DMSO）或甘油百分比
  • 支持一对一、一对多、多对一或更复杂试剂配比，从兼容母板精准移液至干燥或预填液目标孔

Learn More

Downloadable Brochures

Download ↓Echo Liquid Handler Brochure Cover
Download ↓Automated Liquid Handling for Drug Discovery Brochure Cover
Download ↓Echo Software Applications Brochure Cover
Download ↓Echo Qualified Consumables Brochure Cover
Download ↓Full Care Lease-to-Own Program flyer

视频

Echo 声波移液系统

 

Echo 软件

 

Citations

  1. Bashore C et al. Targeted degradation via direct 26S proteasome recruitment. Nat Chem Biol. 2023 Jan;19(1):55-63. Epub 2022 Dec 28. PMID: 36577875
  2. Ma S et al. Transcriptional repression of estrogen receptor alpha by YAP reveals the Hippo pathway as therapeutic target for ER+ breast cancer. Nat Commun. 2022 Feb 25;13(1):1061. PMID: 35217640
  3. Pal R, Seleem MN. Discovery of a novel natural product inhibitor of Clostridioides difficile with potent activity in vitro and in vivo. PLoS One. 2022 Aug 8;17(8):e0267859. PMID: 35939437
  4. Papandreou A et al. Automated High-Content Imaging in iPSC-derived Neuronal Progenitors. SLAS Discov. 2023 Jan 4:S2472-5552(22)13715-9. PMID: 36610640
  5. Riva L et al. Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing. Nature. 2020 Oct;586(7827):113-119. Epub 2020 Jul 24. PMID: 32707573
  1. Li J et al. DRUG-seq Provides Unbiased Biological Activity Readouts for Neuroscience Drug Discovery. ACS Chem Biol. 2022 Jun 17;17(6):1401-1414. Epub 2022 May 4. PMID: 35508359
  2. Nyffeler J et al. Combining phenotypic profiling and targeted RNA-Seq reveals linkages between transcriptional perturbations and chemical effects on cell morphology: Retinoic acid as an example. Toxicol Appl Pharmacol. 2022 Jun 1;444:116032. Epub 2022 Apr 26. PMID: 35483669
  1. Bousgouni V, Bakal C. Quantitative imaging of single-cell phenotypes in cancer cells cultured on hydrogel surfaces. STAR Protoc. 2022 Dec 15;4(1):101942. doi: 10.1016/j.xpro.2022.101942. Epub ahead of print. PMID: 36525347
  2. Denisova OV et al. Development of actionable targets of multi-kinase inhibitors (AToMI) screening platform to dissect kinase targets of staurosporines in glioblastoma cells. Sci Rep. 2022 Aug 13;12(1):13796. doi: 10.1038/s41598-022-18118-7. PMID: 35963891
  3. Ross-Thriepland D et al. Arrayed CRISPR Screening Identifies Novel Targets That Enhance the Productive Delivery of mRNA by MC3-Based Lipid Nanoparticles. SLAS Discov. 2020 Jul;25(6):605-617. doi: 10.1177/2472555220925770. Epub 2020 May 22. PMID: 32441189
  1. Bashore C et al. Targeted degradation via direct 26S proteasome recruitment. Nat Chem Biol. 2023 Jan;19(1):55-63. Epub 2022 Dec 28. PMID: 36577875
  2. Ma S et al. Transcriptional repression of estrogen receptor alpha by YAP reveals the Hippo pathway as therapeutic target for ER+ breast cancer. Nat Commun. 2022 Feb 25;13(1):1061. PMID: 35217640
  3. Pal R, Seleem MN. Discovery of a novel natural product inhibitor of Clostridioides difficile with potent activity in vitro and in vivo. PLoS One. 2022 Aug 8;17(8):e0267859. PMID: 35939437
  4. Papandreou A et al. Automated High-Content Imaging in iPSC-derived Neuronal Progenitors. SLAS Discov. 2023 Jan 4:S2472-5552(22)13715-9. PMID: 36610640
  5. Riva L et al. Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing. Nature. 2020 Oct;586(7827):113-119. Epub 2020 Jul 24. PMID: 32707573
  1. Li J et al DRUG-seq Provides Unbiased Biological Activity Readouts for Neuroscience Drug Discovery. ACS Chem Biol. 2022 Jun 17;17(6):1401-1414. Epub 2022 May 4. PMID: 35508359
  2. Nyffeler J et al. Combining phenotypic profiling and targeted RNA-Seq reveals linkages between transcriptional perturbations and chemical effects on cell morphology: Retinoic acid as an example. Toxicol Appl Pharmacol. 2022 Jun 1;444:116032. Epub 2022 Apr 26. PMID: 35483669
  1. Bousgouni V, Bakal C. Quantitative imaging of single-cell phenotypes in cancer cells cultured on hydrogel surfaces. STAR Protoc. 2022 Dec 15;4(1):101942. doi: 10.1016/j.xpro.2022.101942. Epub ahead of print. PMID: 36525347
  2. Denisova OV et al. Development of actionable targets of multi-kinase inhibitors (AToMI) screening platform to dissect kinase targets of staurosporines in glioblastoma cells. Sci Rep. 2022 Aug 13;12(1):13796. doi: 10.1038/s41598-022-18118-7. PMID: 35963891
  3. Ross-Thriepland D et al. Arrayed CRISPR Screening Identifies Novel Targets That Enhance the Productive Delivery of mRNA by MC3-Based Lipid Nanoparticles. SLAS Discov. 2020 Jul;25(6):605-617. doi: 10.1177/2472555220925770. Epub 2020 May 22. PMID: 32441189

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