Comparing Traditional Aggregation Measurement Techniques to the Valita Aggregation Pure Assay
Aggregation is considered one of the key critical quality attributes (CQA) associated with monoclonal antibodies, especially in process development when thorough assessment of aggregation is crucial.
Preventing protein aggregation in a timely manner is of great importance to the biopharmaceutical industry. However, certain methods like DLS/SLS and HPLC-SEC can take hours to produce results due to longer processing times and lower throughput. When dealing with hundreds or thousands of samples to create a commercially viable cell line, these hours accumulate and add unnecessary complexity to your workflow, ultimately affecting your time to market.
Fortunately, there’s a better way. The Valita Aggregation Pure assay is one of the fastest, easiest, and automatable protein aggregation quantification assays available. In just three simple steps and as little as 15 minutes, you can prepare and measure a full 96-well plate.
The Valita Aggregation Pure Assay vs. HPLC-SEC
When comparing the performance of the Valita Aggregation Pure assay to HPLC-SEC, it becomes obvious that both methods demonstrate a high correlation with each other. The same level of accuracy can still be expected from the Valita Aggregation Pure assay as with the existing method, but with an enhanced throughput and a faster, simpler workflow.
Ranking: Valita Aggregation Pure assay vs HPLC-SEC
% Aggregation: Valita Aggregation Pure assay vs HPLC-SEC
Ranking: Valita Aggregation Pure assay vs HPLC-SEC
Insightful Resources
The Valita Aggregation Pure assay: A rapid and accurate alternative for aggregation quantification of purified monoclonal antibodies
Valita Aggregation Pure Assay Brochure
Let’s Accelerate Your Antibody Discovery and Development
Interested in a demo? Just want to ask a few questions?
We’re here to help, please reach out anytime.
