纳米级流式分析仪

Nanoscale Flow Cytometry
Extracellular Vesicle (EV) Analysis with Flow Cytometry

The Challenges of Extracellular Vesicle Analysis

Counting, determining the size of, and characterizing extracellular vesicles (EVs) gives researchers deeper insights into cell and organ health and disease profiles. However, EVs can be challenging to analyze, owing to their small size and heterogeneity.

The need for standardization

Until now, scientists have had to use multiple techniques to accurately count, characterize and determine the size of EVs, to get the insights they need. As a result, workflows that are time-consuming and have poor repeatability are often required.

Flow Cytometry: Sensitive and Efficient Extracellular Vesicle Analysis

Flow cytometry counts, determines the size of, and characterizes EVs in one system, offering both high throughput and resolution. It can detect distinct EVs in polydisperse populations based on size scatter properties, and cargo and cellular origin based on fluorescence.

Flow Cytometry offers:

Detailed characterization	Quality	Efficiency
Analyze single EVs bias-free with sensitive single particle resolution.	Reproducibly characterize heterogeneous and polydisperse samples.	Collect simultaneous multi-parametric data

Which flow cytometry instrument is right for me?

When choosing a flow cytometry instrument, there are three key factors to consider:

Size	Throughput	Flexibility
What size EV do you want to study?	How many samples do you need to run?	Do you need to have flexibility running cells and EVs?