研究相关FAQs

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Where can I find out about immunotherapy clinical trials?
What is the difference between active immunotherapy and passive immunotherapy?
What are adeno-associated viruses (AAVs) and why are they used as vectors?
What are adenoviruses (Ads) and why are they used as vectors?
How does agent type affect biologics production?
What is antigen specific immunotherapy?
Are all immunotherapies cell-based?
How does biological agent type affect regulatory standards?
How are biologics changing the face of disease research and therapeutics?
What are biologics and how do they differ from traditional pharmaceuticals?
How do biologics drive antibody-directed targeting?
How have biologics revolutionized organ/tissue transplantation and regenerative medicine?
How are biologics being used in adoptive cell therapy (ACT)?
How are biomarkers used for diagnostic screening in immunotherapy?
Which Biomaterials can be used to enhance immunotherapy?
How do cancer cells bypass TCR-mediated T cell recognition?
How is the CAR receptor introduced to the T cell?
What antigens can a CAR-T cell target?
Are CAR-T cells used for therapeutic purposes?
Are there side effects with CAR-T cells?
Where do the cells for cell-based immunotherapies come from?
What components and domains make up a chimeric antigen receptor (CAR)?
What are the key considerations to optimizing viral vector production?
What do I need to consider when selecting a viral vector candidate?
What approaches are being considered to improve therapeutic safety?
What are some of the ways CRISPR can enhance improved therapeutic agents?
How can CRISPR gene therapy impact medicine?
How has CRISPR impacted research when it comes to studying gene alterations and function?
What is the difference between CRISPR and RNAi (RNA interference)?
What is the difference between CRISPR (clustered regularly interspaced short palindromic repeats) and TALENs (transcription-activator-like effector nucleases)?
What is the difference between CRISPR and ZFNs (zinc finger nucleases)?
How can CRISPR-mediated genetic engineering impact industrial productivity and nature?
How can cytokines help boost the immune system?
Why would I deliver foreign nucleic acids into a cell?
What's the difference between chemotherapy, radiation, and immunotherapy?
Is there a difference between exosomes recovered by an isolation reagent kit and ultracentrifugation? How do I determine which protocol is "best"?
Are there different CRISPR-associated system (Cas) proteins?
What is the difference between the different T cell types?
What different types of biologic agents are being researched?
Are there different types of gene therapy?
Are there different types of immunotherapy?
Can diluting biofluids with PBS prior to ultracentrifugation enhance recovery of exosomes?
Are there any drawbacks or side-effects to the use of immunotherapy?
Which diseases have immunotherapies been effective in treating?
What is the endogenous purpose of CRISPR?
What ethical dilemmas need to be considered when working with CRISPR technology?
How can I estimate where my exosome fraction of interest will be?
Can I tell exosomes apart from other microvesicles?
Is there a risk that my exosomes will be damaged during ultracentrifugation?
What role do exosomes play in cancer?
What guidelines are available for working with EVs?
What are the Guidelines for Working with Extracellular Vesicles
What does the immune system do?
What is the future of CAR-T research and therapeutics?
What is the difference between gene therapy and cell therapy?
How can genetic engineering be used to enhance workflows for biologics production?
How is genetic engineering being used to modify biologic agents?
What is half-life and why is it important for immunotherapy drugs?
How does the immune system recognize harmful entities?
What are herpes simplex viruses (HSVs) and why are they used as vectors?
What is the history of chimeric antigen receptors (CARs)?
How are biologics being used in targeted gene therapy?
How are CAR-T cells produced?
How are exosomes counted?
How are exosomes isolated?
How are exosomes visualized and characterized?
How are T cells isolated and expanded?
How are biologic medicines administered?
How do chimeric antigen receptors (CARs) work?
How do you produce a viral vector?
How does a viral vector work?
How does CRISPR/Cas work?
Why don’t I see a pellet after centrifuging my exosomes?
How can immune checkpoint inhibitors be used to boost immunotherapy?
Can immune function be therapeutically restored or enhanced?
How does the immune system eliminate harmful cells?
What happens when the immune system does not function properly?
How can immunosuppressants be used for immunotherapy?
Can immunotherapy be used to slow down aging?
Is there an immunotherapy available for every type of cancer?
How can immunotherapy help with inflammatory bowel disease (IBD)?
Will immunotherapy be successful for treating diseases like HIV/AIDS?
What is the potential of immunotherapy?
Do tumors develop resistance to immunotherapies?
How can adjuvants be improved for immunotherapy?
What is the difference between the innate and adaptive immune systems?
Is there an isolation protocol that tends to yield the most reproducible results?
What are lentiviruses and why are they used as vectors?
How do local tissue environmental conditions affect immune function?
What are the main components of a CRISPR/Cas system?
How much starting material will I need for exosome isolation?
How can I assess the mechanisms of antigen loss to uncover novel immunotherapeutics?
What medium should I use when isolating exosomes using ultracentrifugation and a density gradient?
Are reagent kits and/or microfiltration effective alternatives to differential ultracentrifugation for isolating exosomes?
What is mutational load and how does it apply to immunotherapy?
How can nanoparticles be used for immunotherapy?
What is the difference between non-homologous end joining (NHEJ) and homology-directed repair (HDR)?
How do oncolytic viruses target cancer cells in immunotherapy?
What are the differences between oral- sublingual-, and dermal immunotherapy?
What other types of immune cells are there and how do they contribute to immune-mediated killing mechanisms?
What does PAT mean? \| What does PAT mean?
What are peptide-based vaccines?
What are popular immunotherapy approaches?
Why should I consider k-factor when establishing a protocol for ultracentrifugation?
Protocols for isolating exosomes frequently include differential ultracentrifugation with a density gradient. What benefits does this method offer?
For which applications is it important to quantitate exosome number?
What research is being done on cell-based biologic agents?
What research is being done on molecule-based biologic agents?
What research is being done on tissue-based biologic agents?
Does the broad distribution of EV populations affect resolution from background?
What are retroviruses and why are they used as vectors?
What are the differences between RNA and DNA viruses used in immunotherapy?
What is the role of genetic engineering in biologics production?
What safety considerations need to be taken when producing viral vectors?
How does secondary screening differ from high-throughput screening?
How do I select, expand, and store CAR-T cells?
How can you use single cell analysis for immunotherapy?
How can small molecule drugs help boost the immune system?
Why are stem cells important in gene and cell therapy?
How do I stimulate my cells to induce cytokine expression?
What are some strategies for enhancing local delivery of immunotherapy?
Does ultracentrifugation processing duration correlate with successful isolation of exosomes?
What is the T cell receptor and why is it critical?
What does targeting blood vessels have to do with immunotherapy?
How can tumors be targeted using immunocytokines?
What are the differences between TCRs, TILs, and CAR-Ts in immunotherapy?
What diseases can be treated using newly approved immunotherapies?
Does the type of rotor and tubes I use matter when isolating exosomes?
What types of viruses are commonly used as vectors?
Based on research, how does ultracentrifugation compare to precipitation as an isolation technique?
What are some challenges in developing vaccines for immunotherapy?
Why should I use a vector for gene transfer?
What are the challenges of using viral vectors for therapeutic applications?
How do viral vectors compare to other approaches in terms of efficacy?
What are B cells?
What are biologics? \| What are biologics?
What are chimeric viral vectors?
What are exosomes?
What are exosomes made of?
What are macrophages?
What are neoantigens?
What are PAM sequences?
What are small molecule drugs? \| What are small molecule drugs?
What are stem cells and where do they come from?
What are T cells?
What are viral vectors?
What benefit can analyzing EVs by flow Cytometry give, over more traditional methods like western blotting?
What cargoes do exosomes carry?
What is a biobetter? \| What is a biobetter?
What is a biomarker?
What is a biosimilar? \| What is a biosimilar?
What is a chimeric antigen receptor (CAR)?
What is a guide molecule?
What is a lead compound? \| What is a lead compound?
What is adoptive cell transfer?
What is an antibody? \| What is an antibody?
What is an antigen? \| What is an antigen?
What is Bacillus Calmette-Guerin?
What is cell therapy? \| What is cell therapy?
What is cellular immunotherapy?
What is combination therapy?
What is CRISPR?
What is denaturation and what causes it?
What is gene therapy? \| What is gene therapy?
What is high-throughput screening (HTS)?
What is immune evasion?
What is immunogenicity? \| What is immunogenicity?
What is immuno-oncology?
What is immunotherapy?
What is targeted immunotherapy?
What is the function of exosomes?
What is the future of CRISPR?
How can I differentiate between particulate in the sample, the sample probe, or the sheath solution?
What are typical protein, DNA, and RNA yields from exosomes isolated by ultracentrifugation?

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