离心技巧与行业洞察

spINSIGHTS logo
贝克曼库尔特应用科学家Akash Bhattacharya博士、Shawn Sternisha博士和Ross VerHeul与您分享离心技巧与行业洞察。
application note ELEVATING EV Characterization with Analytical Ultracentrifugation (AUC)

Elevating EV Characterization with Analytical Ultracentrifugation

EVs are an exciting area of research. Nonetheless, characterizing EVs remains a challenge due to their inherent heterogeneity.
DGUC reveals the nature of heterogeneity in multiple LNP formulations

DGUC and Lipid Nanoparticles

Density gradient ultracentrifugation can be used to purify fractions of loaded lipid nanoparticles.
Advantages of UC for AAV purification, Process Quality: Yield and Purity

DGUC vs AC

Density Gradient Ultracentrifugation is advantaged over affinity chromatography for viral vector purification.
spINSIGHT Ultracentrifugation is-preferred for high purity EV isolation

High-Purity EV isolation

Ultracentrifugation (UC) is broadly considered the gold standard for EV purification due to its capacity to reproducibly isolate specific subpopulations of EVs.
img3

Cell Culture Optimization using data from AUC

Discover how data from AUC can help improve AAV Production Yield.
image

Multiwavelength AUC characterization & QC

Discover how data from AUC determines dose optimization in therapeutic liposomes.
img5

Why use AUC?

Getting comfortable with Analytical Ultracentrifugation.
img1

Sapphire vs. Quartz

Sapphire windows provide better data than quartz windows for high speed AUC applications, such as peptides and small molecules.

Density Gradient Ultracentrifugation (DGUC)

How can I prepare consistent density gradients for reproducibly purifying samples via ultracentrifugation?

AAV Analysis with AUC

AUC provides high-resolution data on AAV particle quality & fullness.

Seamless Protocol Transfer

Discover the ways to transfer an existing centrifugation protocol to a new rotor, bottle, or tube. 

Optima AUC Advantages

Discover the advantages of using the Optima AUC to improve your data quality and workflow efficiency.

Consumable Purity Grades

Discover the difference between sterile and certified free consumables, then determine the necessary purity grade for your application.

联系我们